Hoch-Campbell ethylenimine synthesis
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In organic chemistry the Hoch-Campbell ethylenimine synthesis is a method for constructing ethyleneimines from oximes. The oxime is treated with Grignard reagents:[1][2][3][4]
![Hoch-Campbell Ethylenimine Synthesis](http://178.128.105.246/cars-http-upload.wikimedia.org/wikipedia/commons/thumb/a/ab/Hoch-Campbell_Ethylenimine_Synthesis.svg/399px-Hoch-Campbell_Ethylenimine_Synthesis.svg.png)
References
[edit]- ^ Hoch, Compt. rend., 196, 1865 (1934); (a), ibid., aOS, 799 (1936); (e), ibid., 204, 358 (1937).
- ^ Kenneth N. Campbell; James F. Mckenna (1939). "The action of Grignard reagents on oximes. i. The action of phenylmagnesium bromide on mixed ketoximes". Journal of Organic Chemistry. 4 (2): 198–205. doi:10.1021/jo01214a012.
- ^ Kenneth N. Campbell; Barbara Knapp Campbell; Elmer Paul Chaput (1943). "The reaction of Grignard reagents with oximes. ii. The action of aryl grignard reagents with mixed ketoximes". Journal of Organic Chemistry. 8 (1): 99–102. doi:10.1021/jo01189a015.
- ^ Kenneth N. Campbell; Barbara K. Campbell; James F. Mckenna; Elmer Paul Chaput (1943). "The action of Grignard reagents on oximes. iii. The mechanism of the action of arylmagnesium halides on mixed ketoximes. A new synthesis of ethyleneimines". Journal of Organic Chemistry. 8: 103–9. doi:10.1021/jo01189a016.