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Review
. 2022 Dec;40(12):2450-2462.
doi: 10.55563/clinexprheumatol/9t3ul2. Epub 2022 Oct 10.

Chest high-resolution computed tomography in primary Sjögren's syndrome: an up-to-date primer for rheumatologists

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Free article
Review

Chest high-resolution computed tomography in primary Sjögren's syndrome: an up-to-date primer for rheumatologists

Lorenzo Cereser et al. Clin Exp Rheumatol. 2022 Dec.
Free article

Abstract

Pulmonary manifestations, including airway involvement and interstitial lung disease, are the most frequent extra-glandular complications of primary Sjögren's syndrome (pSS). Chest high-resolution computed tomography (HRCT) is a cornerstone of pulmonary diagnostic imaging, aiming to detect, characterise, and quantify such conditions. In patients with pSS-related lung abnormalities, HRCT proved helpful in various clinical scenarios, including baseline and follow-up evaluation, assessment of superimposed infections, suspected progressive interstitial lung diseases, and acute exacerbation. This review aims to provide a primer for rheumatologists on chest HRCT, illustrating the up-to-date technique, imaging findings, and clinical indications in pSS and highlighting the importance of rheumatologist-radiologist constructive collaboration in the clinical management of such patients.

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