Hemoglobin subunit beta (Q424422)

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mammalian protein found in Homo sapiens
  • hemoglobin beta subunit
  • beta globin chain
  • hemoglobin, beta
  • Beta-globin
  • Hemoglobin beta chain
  • HBB
  • hemoglobin subunit beta
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Language Label Description Also known as
English
Hemoglobin subunit beta
mammalian protein found in Homo sapiens
  • hemoglobin beta subunit
  • beta globin chain
  • hemoglobin, beta
  • Beta-globin
  • Hemoglobin beta chain
  • HBB
  • hemoglobin subunit beta

Statements

molecular function
protein binding
determination method
IPI
11 references
retrieved
31 October 2017
stated in
A human recombinant haemoglobin designed for use as a blood substitute
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
IPI
retrieved
31 October 2017
stated in
Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
IPI
retrieved
31 October 2017
stated in
Control of heme reactivity by diffusion: structural basis and functional characterization in hemoglobin mutants
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
IPI
retrieved
31 October 2017
stated in
A human protein-protein interaction network: a resource for annotating the proteome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
IPI
retrieved
31 October 2017
stated in
Structural and functional properties of human hemoglobins reassembled after synthesis in Escherichia coli
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
IPI
retrieved
31 October 2017
stated in
The use of electron tomography for structural analysis of disordered protein arrays
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
IPI
retrieved
31 October 2017
stated in
Separation of zeta (zeta) and various gamma (gamma) chains of human embryonic hemoglobin Portland I by reverse-phase high-performance liquid chromatography
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
IPI
retrieved
31 October 2017
stated in
Expression, purification, and characterization of human hemoglobins Gower-1 (zeta(2)epsilon(2)), Gower-2 (alpha(2)epsilon(2)), and Portland-2 (zeta(2)beta(2)) assembled in complex transgenic-knockout mice
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
IPI
retrieved
31 October 2017
stated in
Crystal structure of deoxy-human hemoglobin beta6 Glu --> Trp. Implications for the structure and formation of the sickle cell fiber
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
IPI
retrieved
31 October 2017
stated in
Genetically crosslinked hemoglobin: a structural study
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
IPI
retrieved
31 October 2017
stated in
Modulation of ligand binding in engineered human hemoglobin distal pocket
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
IPI
cell component
hemoglobin complex
determination method
NAS
IDA
TAS
IEA
5 references
retrieved
31 October 2017
stated in
Structure of the EF corner favors deamidation of asparaginyl residues in hemoglobin: the example of Hb La Roche-sur-Yon [beta 81 (EF5) Leu----His]
GOA
curator
UniProt
UniProt protein ID
P68871
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
TAS
retrieved
31 October 2017
stated in
Ancient origins of nitric oxide signaling in biological systems
GOA
curator
UniProt
UniProt protein ID
P68871
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
NAS
retrieved
31 October 2017
stated in
A novel beta-globin structural mutant, Hb Brescia (beta 114 Leu-Pro), causing a severe beta-thalassemia intermedia phenotype
GOA
curator
UniProt
UniProt protein ID
P68871
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
NAS
retrieved
31 October 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
IEA
retrieved
31 October 2017
stated in
Peroxidase activity of hemoglobin-haptoglobin complexes: covalent aggregation and oxidative stress in plasma and macrophages
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68871&geneProductId=UniProtKB:P68871
determination method
IDA
biological process

Identifiers

Freebase ID
/m/03bxl22
0 references
PDB structure ID
 
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