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Aldehyde oxidase 1

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(Redirected from AOX1)

AOX1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesAOX1, AO, AOH1, aldehyde oxidase 1
External IDsOMIM: 602841; MGI: 88035; HomoloGene: 68165; GeneCards: AOX1; OMA:AOX1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001159

NM_009676

RefSeq (protein)

NP_001150

NP_033806

Location (UCSC)Chr 2: 200.59 – 200.68 MbChr 1: 58.07 – 58.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Aldehyde oxidase 1 is an enzyme that in humans is encoded by the AOX1 gene.[5][6]

Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide.[5]

Clinical significance

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Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis.[6]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000138356Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063558Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: aldehyde oxidase 1".
  6. ^ a b Berger R, Mezey E, Clancy KP, Harta G, Wright RM, Repine JE, Brown RH, Brownstein M, Patterson D (March 1995). "Analysis of aldehyde oxidase and xanthine dehydrogenase/oxidase as possible candidate genes for autosomal recessive familial amyotrophic lateral sclerosis". Somat. Cell Mol. Genet. 21 (2): 121–31. doi:10.1007/BF02255787. PMID 7570184. S2CID 24691533.
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Further reading

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