Hepatitis B virus infection: current status
P Ocama, CK Opio, WM Lee�- The American journal of medicine, 2005 - Elsevier
Hepatitis B virus currently infects more than 400 million people worldwide. Despite the
availability of hepatitis B vaccine, the overall prevalence of hepatitis B virus infection has
declined little in recent years. Hepatitis B virus causes liver injury by an immune response
against the virus-infected liver cells and is not directly cytopathic, although
immunosuppression appears to enhance replication and lead to direct cytotoxicity. The
interplay of the host immune response and the virus's ability to replicate is a prime�…
availability of hepatitis B vaccine, the overall prevalence of hepatitis B virus infection has
declined little in recent years. Hepatitis B virus causes liver injury by an immune response
against the virus-infected liver cells and is not directly cytopathic, although
immunosuppression appears to enhance replication and lead to direct cytotoxicity. The
interplay of the host immune response and the virus's ability to replicate is a prime�…
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