Tiemonium iodide

Tiemonium iodide
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	A03AB17 (WHO) ;
Identifiers
	IUPAC name 4-[3-hydroxy-3-phenyl-3-(2-thienyl)propyl]-4-methylmorpholin-4-ium iodide;
CAS Number	144-12-7;
PubChem CID	72142;
ChemSpider	65116;
UNII	FZ2LZ7U304;
KEGG	D01201;
CompTox Dashboard (EPA)	DTXSID00875078 ;
ECHA InfoCard	100.005.106
Chemical and physical data
Formula	C18H24INO2S
Molar mass	445.36 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[N+]1(CCOCC1)CCC(C2=CC=CC=C2)(C3=CC=CS3)O.[I-];
	InChI InChI=1S/C18H24NO2S.HI/c1-19(11-13-21-14-12-19)10-9-18(20,17-8-5-15-22-17)16-6-3-2-4-7-16;/h2-8,15,20H,9-14H2,1H3;1H/q+1;/p-1; Key:IOFXEUZPIIUQAG-UHFFFAOYSA-M;

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Tiemonium iodide is an antimuscarinic. It is poorly absorbed from the gut. The active moiety is tiemonium, a quaternary ammonium cation.^[1]

References

^ Scoular IT, Monks A, Burgess C, Turner P (1977). "Human studies on the bioavailability of a quaternary ammonium compounds, tiemonium iodide and tiemonium methosulphate". Current Medical Research and Opinion. 4 (10): 732–8. doi:10.1185/03007997609112009. PMID 1052164.

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[1] Scoular IT, Monks A, Burgess C, Turner P (1977). "Human studies on the bioavailability of a quaternary ammonium compounds, tiemonium iodide and tiemonium methosulphate". Current Medical Research and Opinion. 4 (10): 732–8. doi:10.1185/03007997609112009. PMID 1052164.

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