Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Mar 1:16:100.
doi: 10.1186/s12879-016-1389-2.

Inflammatory arthritis in HIV positive patients: A practical guide

T Adizie  1 , R J Moots  2   3 , B Hodkinson  4 , N French  5 , A O Adebajo  6
Affiliations
Review

Inflammatory arthritis in HIV positive patients: A practical guide

T Adizie et al. BMC Infect Dis. .

Abstract

Background: Musculoskeletal manifestations of the human immunodeficiency virus (HIV) have been described since the outset of the global HIV epidemic. Articular syndromes that have been described in association with HIV include HIV-associated arthropathy, seronegative spondyloarthropathies (SPA) (reactive arthritis, psoriatic arthritis (PsA) and undifferentiated SPA), rheumatoid arthritis (RA) and painful articular syndrome.

Methods: We carried out a computer-assisted search of PubMed for the medical literature from January 1981 to January 2015 using the keywords HIV, acquired immune-deficiency syndrome, rheumatic manifestations, arthritis, spondyloarthropathy, anti-TNF and disease modifying antirheumatic drugs. Only English language literature was included and only studies involving adult human subjects were assessed.

Results: There are challenges in the management of inflammatory arthritis in patients who are HIV-positive, including difficulties in the assessment of disease activity and limited information on the safety of immunosuppressive drugs in these individuals.

Conclusions: This review focuses on the clinical characteristics of the inflammatory articular syndromes that have been described in association with HIV infection and discusses the therapeutic options for these patients.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Flowchart of study identification and selection
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Winchester R, Bernstein D, Fischer H, Enlow R, Solomon G. The co-occurrence of Reiter’s syndrome and acquired immunodeficiency. Ann Intern Med. 1987;106:19–26. doi: 10.7326/0003-4819-106-1-19. - DOI - PubMed
    1. UNAIDS. Global Report: UNAIDS Report on the Global AIDS Epidemic. 2012. Available from http://www.unaids.org/en/media/unaids/contentassets/documents/epidemiolo....
    1. Kaddu-Mukasa M, Ssekasanvu E, Ddumba E, Thomas D, Katabira ET. Rheumatic manifestations among HIV positive adults attending the Infectious disease clinic at Mulago hospital. Afr Health Sci. 2011;11(1):24–9. - PMC - PubMed
    1. Kole AK, Roy R, Kole D. Musculoskeletal and rheumatological disorders in HIV infection: Experience in a tertiary referral center. Indian J Sex Transm Dis. 2013;34(2):107–12. doi: 10.4103/0253-7184.120542. - DOI - PMC - PubMed
    1. Plate A-M, Boyle B. Musculoskeletal Manifestations of HIV. AIDS Read. 2003;13(2):62. - PubMed

Substances