P2X purinoceptor 5 is a protein in humans that is encoded by the P2RX5 gene.[5][6]

P2RX5
Identifiers
AliasesP2RX5, LRH-1, P2X5, P2X5R, purinergic receptor P2X 5
External IDsOMIM: 602836; MGI: 2137026; HomoloGene: 1924; GeneCards: P2RX5; OMA:P2RX5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_175081
NM_001204519
NM_001204520
NM_002561
NM_175080

NM_033321
NM_001376982
NM_001376983

RefSeq (protein)

NP_001191448
NP_001191449
NP_002552
NP_778255

n/a

Location (UCSC)Chr 17: 3.67 – 3.7 MbChr 11: 73.05 – 73.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Four transcript variants encoding distinct isoforms have been identified for this gene.[6]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000083454Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000005950Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Le KT, Paquet M, Nouel D, Babinski K, Seguela P (Jan 1998). "Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system". FEBS Lett. 418 (1–2): 195–9. doi:10.1016/S0014-5793(97)01380-X. PMID 9414125. S2CID 42070561.
  6. ^ a b "Entrez Gene: P2RX5 purinergic receptor P2X, ligand-gated ion channel, 5".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.