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LIME1

From Wikipedia, the free encyclopedia
LIME1
Identifiers
AliasesLIME1, LIME, LP8067, dJ583P15.4, Lck interacting transmembrane adaptor 1
External IDsOMIM: 609809; MGI: 1919949; HomoloGene: 56785; GeneCards: LIME1; OMA:LIME1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_017806
NM_001305654
NM_001305655

NM_023684

RefSeq (protein)

NP_001292583
NP_001292584
NP_060276

NP_076173

Location (UCSC)n/aChr 2: 181.02 – 181.03 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Lck-interacting transmembrane adapter 1 is a protein that in humans is encoded by the LIME1 gene.[4][5]

LIME1 is a raft-associated transmembrane adaptor phosphoprotein that is preferentially expressed in hemopoietic cells, particularly T cells.[6][5]

References

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  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000090077Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  5. ^ a b "Entrez Gene: LIME1 Lck interacting transmembrane adaptor 1".
  6. ^ Brdicková N, Brdicka T, Angelisová P, Horváth O, Spicka J, Hilgert I, Paces J, Simeoni L, Kliche S, Merten C, Schraven B, Horejsí V (November 2003). "LIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling". J Exp Med. 198 (10): 1453–62. doi:10.1084/jem.20031484. PMC 2194115. PMID 14610046.

Further reading

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