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VCPIP1

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VCPIP1
Identifikatori
AliasiVCPIP1
Vanjski ID-jeviOMIM: 611745 MGI: 1917925 HomoloGene: 11814 GeneCards: VCPIP1
Lokacija gena (čovjek)
Hromosom 8 (čovjek)
Hrom.Hromosom 8 (čovjek)[1]
Hromosom 8 (čovjek)
Genomska lokacija za VCPIP1
Genomska lokacija za VCPIP1
Bend8q13.1Početak66,628,487 bp[1]
Kraj66,667,231 bp[1]
Lokacija gena (miš)
Hromosom 1 (miš)
Hrom.Hromosom 1 (miš)[2]
Hromosom 1 (miš)
Genomska lokacija za VCPIP1
Genomska lokacija za VCPIP1
Bend1|1 A2Početak9,788,847 bp[2]
Kraj9,818,607 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija thiol-dependent deubiquitinase
GO:0070122 peptidase activity
cysteine-type peptidase activity
hydrolase activity
Ćelijska komponenta citoplazma
Golgi stack
Golđijev aparat
Endoplazmatski retikulum
endoplasmic reticulum lumen
Biološki proces endoplasmic reticulum membrane fusion
protein K48-linked deubiquitination
Golgi organization
protein ubiquitination
protein K11-linked deubiquitination
Proteoliza
Golgi reassembly
GO:0007067 Mitoza
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_025054

NM_173443

RefSeq (bjelančevina)

NP_079330

NP_775619

Lokacija (UCSC)Chr 8: 66.63 – 66.67 MbChr 1: 9.79 – 9.82 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Deubikvitinirajući protein VCIP135 je protein koji je kod ljudi kodiran genom VCPIP1.[5][6][7]

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 1.222 aminokiseline, а molekulska težina Da. 134 321[8]

1020304050
MSQPPPPPPPLPPPPPPPEAPQTPSSLASAAASGGLLKRRDRRILSGSCP
DPKCQARLFFPASGSVSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLR
NALLGVTGAPKKNTELVKVMGLSNYHCKLLSPILARYGMDKQTGRAKLLR
DMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHDTLEDIKR
ANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHL
ARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLH
RPIILLDSLSGMRSSGDYSATFLPGLIPAEKCTGKDGHLNKPICIAWSSS
GRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLIKKYIKLEEDGGCVIG
GDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQP
EEVTAAAKKAVMDNRLHKCLLCGALSELHVPPEWLAPGGKLYNLAKSTHG
QLRTDKNYSFPLNNLVCSYDSVKDVLVPDYGMSNLTACNWCHGTSVRKVR
GDGSIVYLDGDRTNSRSTGGKCGCGFKHFWDGKEYDNLPEAFPITLEWGG
RVVRETVYWFQYESDSSLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVHT
ILHQTAKKNPDDYTPVNIDGAHAQRVGDVQGQESESQLPTKIILTGQKTK
TLHKEELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPST
IRDGPSSAPATPTKAPYSPTTSKEKKIRITTNDGRQSMVTLKSSTTFFEL
QESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEI
LKSKAEGGQSAAAHSAHTVKQEDIAVTGKLSSKELQEQAEKEMYSLCLLA
TLMGEDVWSYAKGLPHMFQQGGVFYSIMKKTMGMADGKHCTFPHLPGKTF
VYNASEDRLELCVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPS
HGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASGNPHLDPRARETSV
VRKHNTGTDFSNSSTKTEPSVFTASSSNSELIRIAPGVVTMRDGRQLDPD
LVEAQRKKLQEMVSSIQASMDRHLRDQSTEQSPSDLPQRKTEVVSSSAKS
GSLQTGLPESFPLTGGTENLNTETTDGCVADALGAAFATRSKAQRGNSVE
ELEEMDSQDAEMTNTTEPMDHS

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000175073 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045210 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T, Nakayama M, Nakajima D, Kikuno R, Ohara O (Apr 2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 8 (2): 85–95. doi:10.1093/dnares/8.2.85. PMID 11347906.
  6. ^ Ficarro S, Chertihin O, Westbrook VA, White F, Jayes F, Kalab P, Marto JA, Shabanowitz J, Herr JC, Hunt DF, Visconti PE (Mar 2003). "Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation". The Journal of Biological Chemistry. 278 (13): 11579–89. doi:10.1074/jbc.M202325200. PMID 12509440.
  7. ^ "Entrez Gene: VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1".
  8. ^ "UniProt, Q96JH7" (jezik: engleski). Pristupljeno 22. 9. 2021.

Dopunska literatura

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