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AGPAT3

From Wikipedia, the free encyclopedia
AGPAT3
Identifiers
AliasesAGPAT3, LPAAT-GAMMA1, LPAAT3, 1-acylglycerol-3-phosphate O-acyltransferase 3, 1-AGPAT 3
External IDsOMIM: 614794; MGI: 1336186; HomoloGene: 10591; GeneCards: AGPAT3; OMA:AGPAT3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001037553
NM_020132
NM_001369878
NM_001369880
NM_001369881

NM_053014

RefSeq (protein)

NP_001032642
NP_064517
NP_001356807
NP_001356809
NP_001356810

Location (UCSC)Chr 21: 43.87 – 43.99 MbChr 10: 78.11 – 78.19 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

1-acyl-sn-glycerol-3-phosphate acyltransferase gamma is an enzyme that in humans is encoded by the AGPAT3 gene.[5]

The protein encoded by this gene is an acyltransferase (specifically, 1-acylglycerol-3-phosphate O-acyltransferase) that converts lysophosphatidic acid (1-acyl-sn-glycerol 3-phosphate) into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two transcript variants encoding the same protein have been found for this gene.[5]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000160216Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001211Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3".
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Further reading

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