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GFRα

From Wikipedia, the free encyclopedia
Glial cell line-derived neurotrophic factor receptor
Identifiers
SymbolGFRα
PfamPF02351
InterProIPR003438
Membranome44
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

The GDNF family receptor-α (GFRα) proteins are a group of co-receptors which form complexes with GDNF-family ligands (GFLs) to activate RET, the receptor of the GFLs.[1] The GFRα co-receptors include the following:

References

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  1. ^ Enokido Y, de Sauvage F, Hongo JA, Ninkina N, Rosenthal A, Buchman VL, Davies AM (September 1998). "GFR alpha-4 and the tyrosine kinase Ret form a functional receptor complex for persephin". Current Biology. 8 (18): 1019–22. doi:10.1016/s0960-9822(07)00422-8. PMID 9740802. S2CID 1669891.