ATL-444
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(IUPAC) ime | |||
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(1S,3R)-1-[2-(6-amino-9-prop-2-inilpurin-2-ol)etinil]-3-metilcikloheksan-1-ol | |||
Klinički podaci | |||
Identifikatori | |||
ATC kod | nije dodeljen | ||
PubChem[1][2] | 11616539 | ||
ChemSpider[3] | 9791288 | ||
Hemijski podaci | |||
Formula | C17H19N5O | ||
Mol. masa | 309,365 g/mol | ||
SMILES | eMolekuli & PubHem | ||
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Farmakoinformacioni podaci | |||
Trudnoća | ? | ||
Pravni status |
ATL-444 je lek koji deluje kao potentan i selektivan antagonist adenozinskih receptora A1 i A2A. On se koristi za studiranje uloge adenozinskog receptorskog sistema u pojačavanju dejstva kokaina.[4]
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Doyle, S. E.; Breslin, F. J.; Rieger, J. M.; Beauglehole, A.; Lynch, W. J. (2012). „Time and sex-dependent effects of an adenosine A2A/A1 receptor antagonist on motivation to self-administer cocaine in rats”. Pharmacology Biochemistry and Behavior 102 (2): 257–263. DOI:10.1016/j.pbb.2012.05.001. PMC 3383440. PMID 22579716.