Anti-retroviral antibody FcγR-mediated effector functions (Q39108744)

9 September 2017

title

Anti-retroviral antibody FcγR-mediated effector functions (English)

1 reference

9 September 2017

Jeffrey V Ravetch

1 reference

9 September 2017

Stylianos Bournazos

1 reference

9 September 2017

publication date

1 January 2017

1 reference

9 September 2017

published in

Immunological Reviews

1 reference

9 September 2017

volume

275

1 reference

9 September 2017

1 reference

9 September 2017

page(s)

285-295

1 reference

Passive antibody therapy for infectious diseases

9 September 2017

cites work

1 reference

Effect of palivizumab prophylaxis on subsequent recurrent wheezing in preterm infants

21 January 2018

1 reference

Raxibacumab for the treatment of inhalational anthrax

21 January 2018

1 reference

Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb

21 January 2018

1 reference

Safety and pharmacokinetics of a human monoclonal antibody to rabies virus: a randomized, dose-escalation phase 1 study in adults

21 January 2018

1 reference

Treatment with monoclonal antibodies against Clostridium difficile toxins

21 January 2018

1 reference

Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection

21 January 2018

1 reference

Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.

21 January 2018

1 reference

HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption

21 January 2018

1 reference

Antibodies in HIV-1 vaccine development and therapy

21 January 2018

1 reference

Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm

21 January 2018

1 reference

Antibody-based protection against HIV infection by vectored immunoprophylaxis

21 January 2018

1 reference

Fc receptor but not complement binding is important in antibody protection against HIV.

21 January 2018

1 reference

Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies

21 January 2018

1 reference

A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges

21 January 2018

1 reference

HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

21 January 2018

1 reference

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

21 January 2018

1 reference

Functional and clinical consequences of Fc receptor polymorphic and copy number variants.

21 January 2018

1 reference

Fcgamma receptors: old friends and new family members

21 January 2018

1 reference

High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

21 January 2018

1 reference

The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex

21 January 2018

1 reference

Organization of the human and mouse low-affinity Fc gamma R genes: duplication and recombination

21 January 2018

1 reference

Genomic organization of classical human low-affinity Fcgamma receptor genes

21 January 2018

1 reference

Fcgamma receptors as regulators of immune responses

21 January 2018

1 reference

Divergent immunoglobulin g subclass activity through selective Fc receptor binding

21 January 2018

1 reference

The coordination of signaling during Fc receptor-mediated phagocytosis

21 January 2018

1 reference

Type I and type II Fc receptors regulate innate and adaptive immunity

21 January 2018

1 reference

Tyrosine-containing motif that transduces cell activation signals also determines internalization and antigen presentation via type III receptors for IgG

21 January 2018

1 reference

Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases

21 January 2018

1 reference

Fcgamma receptor-mediated mitogen-activated protein kinase activation in monocytes is independent of Ras.

21 January 2018

1 reference

Phosphatidylinositol-3 kinase activation induced upon Fc gamma RIIIA-ligand interaction

21 January 2018

1 reference

Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: regulation upon CD16 ligand binding

21 January 2018

1 reference

Association of the high-affinity receptor for IgG (Fc gamma RI) with the gamma subunit of the IgE receptor

21 January 2018

1 reference

Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI.

21 January 2018

1 reference

Molecular basis for immune complex recognition: a comparison of Fc-receptor structures

21 January 2018

1 reference

Mechanisms for regulating expression of membrane isoforms of Fc gamma RIII (CD16).

21 January 2018

1 reference

Cytoplasmic domain heterogeneity and functions of IgG Fc receptors in B lymphocytes

21 January 2018

1 reference

Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

21 January 2018

1 reference

Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling

21 January 2018

1 reference

A complementary DNA clone for a macrophage-lymphocyte Fc receptor

21 January 2018

1 reference

Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes

21 January 2018

1 reference

CR3 (Mac-1, alpha M beta 2, CD11b/CD18) and Fc gamma RIII cooperate in generation of a neutrophil respiratory burst: requirement for Fc gamma RIII and tyrosine phosphorylation

21 January 2018

1 reference

Mouse model recapitulating human Fcγ receptor structural and functional diversity

21 January 2018

1 reference

Structural Characterization of Anti-Inflammatory Immunoglobulin G Fc Proteins

21 January 2018

1 reference

General mechanism for modulating immunoglobulin effector function

21 January 2018

1 reference

B cells and CD22 are dispensable for the immediate antiinflammatory activity of intravenous immunoglobulins in vivo

21 January 2018

1 reference

Intravenous immunoglobulin therapy: how does IgG modulate the immune system?

21 January 2018

1 reference

Identification of a receptor required for the anti-inflammatory activity of IVIG.

21 January 2018

1 reference

Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway.

21 January 2018

1 reference

Protection in antibody- and T cell-mediated autoimmune diseases by antiinflammatory IgG Fcs requires type II FcRs

21 January 2018

1 reference

Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor Fc RI

21 January 2018

1 reference

The absence of IgE antibody-mediated augmentation of immune responses in CD23-deficient mice

21 January 2018

1 reference

IgE-mediated enhancement of CD4+ T cell responses in mice requires antigen presentation by CD11c+ cells and not by B cells

21 January 2018

1 reference

Two species of human Fc epsilon receptor II (Fc epsilon RII/CD23): tissue-specific and IL-4-specific regulation of gene expression

21 January 2018

2 references

21 January 2018

12 December 2020

Anti-HA Glycoforms Drive B Cell Affinity Selection and Determine Influenza Vaccine Efficacy

1 reference

Analysis of the antibody structure based on high-resolution crystallographic studies

21 January 2018

1 reference

In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner

21 January 2018

1 reference

Impact of differential glycosylation on IgG activity

21 January 2018

1 reference

Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity.

21 January 2018

1 reference

Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions

21 January 2018

1 reference

Selective blockade of the inhibitory Fcgamma receptor (FcgammaRIIB) in human dendritic cells and monocytes induces a type I interferon response program

21 January 2018

1 reference

hCAP-18, a cathelin/pro-bactenecin-like protein of human neutrophil specific granules

21 January 2018

1 reference

Antibiotic peptides and serine protease homologs in human polymorphonuclear leukocytes: defensins and azurocidin

21 January 2018

1 reference

Expression of the neutrophil elastase gene during human bone marrow cell differentiation

21 January 2018

1 reference

Platelet-leukocyte interactions in thrombosis

21 January 2018

1 reference

Involvement of GD3 in platelet activation. A novel association with Fcgamma receptor.

21 January 2018

1 reference

FcR gamma chain deletion results in pleiotrophic effector cell defects

21 January 2018

1 reference

Targeting natural killer cells in cancer immunotherapy

21 January 2018

1 reference

Innate or adaptive immunity? The example of natural killer cells

21 January 2018

1 reference

Modulation of immune complex-induced inflammation in vivo by the coordinate expression of activation and inhibitory Fc receptors.

21 January 2018

1 reference

Selective suppression of interleukin-12 induction after macrophage receptor ligation

21 January 2018

1 reference

Autonomous phagosomal degradation and antigen presentation in dendritic cells

21 January 2018

1 reference

syk protein tyrosine kinase regulates Fc receptor gamma-chain-mediated transport to lysosomes

21 January 2018

1 reference

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

21 January 2018

1 reference

Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells

21 January 2018

1 reference

Inducing tumor immunity through the selective engagement of activating Fcgamma receptors on dendritic cells

21 January 2018

1 reference

IgG2a-mediated enhancement of antibody responses is dependent on FcRgamma+ bone marrow-derived cells.

21 January 2018

1 reference

Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization

21 January 2018

1 reference

Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect

21 January 2018

1 reference

Deletion of fcgamma receptor IIB renders H-2(b) mice susceptible to collagen-induced arthritis

21 January 2018

1 reference

Distinct cell-specific control of autoimmunity and infection by FcgammaRIIb

21 January 2018

1 reference

FcgammaRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis.

21 January 2018

1 reference

Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) mice

21 January 2018

1 reference

A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. I. Regulatory FCGR2B polymorphisms and their association with systemic lupus erythematosus

21 January 2018

1 reference

Impaired inhibitory Fcgamma receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy

21 January 2018

1 reference

The role of Fc-FcγR interactions in IgG-mediated microbial neutralization

21 January 2018

1 reference

A mouse model for HIV-1 entry

21 January 2018

1 reference

Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo

21 January 2018

1 reference

Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity

21 January 2018

1 reference

Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice

21 January 2018

1 reference

Passive immunotherapy in simian immunodeficiency virus-infected macaques accelerates the development of neutralizing antibodies

21 January 2018

1 reference

Passive neutralizing antibody controls SHIV viremia and enhances B cell responses in infant macaques.

21 January 2018

1 reference

HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1.

21 January 2018

1 reference

Impact of Fc{gamma}RIIa-Fc{gamma}RIIIa polymorphisms and KRAS mutations on the clinical outcome of patients with metastatic colorectal cancer treated with cetuximab plus irinotecan.

21 January 2018

1 reference

FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab.

21 January 2018

1 reference

FcγR2A and 3A polymorphisms predict clinical outcome of trastuzumab in both neoadjuvant and metastatic settings in patients with HER2-positive breast cancer

21 January 2018

1 reference

Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions

21 January 2018

1 reference

Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts

21 January 2018

1 reference

A 13-amino-acid motif in the cytoplasmic domain of FcγRIIB modulates B-cell receptor signalling

21 January 2018

1 reference

The high affinity Fc gamma receptor (CD64) induces phagocytosis in the absence of its cytoplasmic domain: the gamma subunit of Fc gamma RIIIA imparts phagocytic function to Fc gamma RI

21 January 2018

1 reference

12 December 2020

SHIP recruitment attenuates Fc gamma RIIB-induced B cell apoptosis

1 reference

12 December 2020

Fc gamma RIIIA-mediated signaling involves src-family lck in human natural killer cells.

1 reference

12 December 2020

Inducible binding of bioactive cathepsin G to the cell surface of neutrophils. A novel mechanism for mediating extracellular catalytic activity of cathepsin G

1 reference

12 December 2020

FcγRIIb controls bone marrow plasma cell persistence and apoptosis

1 reference

12 December 2020

Regulation of B cell functions by the sialic acid-binding receptors siglec-G and CD22.

1 reference

12 December 2020

Increased expression of FcgammaRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus

1 reference

12 December 2020

Phosphatidylinositol 3-kinase and ERK are required for NF-kappaB activation but not for phagocytosis

1 reference

12 December 2020

Involvement of phosphatidylinositol 3-kinase in Fc gamma receptor signaling.

1 reference

12 December 2020

Clustering of the high affinity Fc receptor for immunoglobulin G (Fc gamma RI) results in phosphorylation of its associated gamma-chain

1 reference

12 December 2020

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

1 reference

12 December 2020

Cell surface recycling of internalized antigen permits dendritic cell priming of B cells

1 reference

12 December 2020

The Fc gamma RI receptor signals through the activation of hck and MAP kinase

1 reference

12 December 2020

IL-10 stimulates monocyte Fc gamma R surface expression and cytotoxic activity. Distinct regulation of antibody-dependent cellular cytotoxicity by IFN-gamma, IL-4, and IL-10

1 reference

12 December 2020

Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus

1 reference

12 December 2020

IFN-γ induces the high-affinity Fc receptor I for IgG (CD64) on human glomerular mesangial cells

1 reference

12 December 2020

Basis of the intrinsic flexibility of the Cε3 domain of IgE

1 reference

12 December 2020

Protein-tyrosine kinase p72syk in Fc gamma RI receptor signaling

1 reference

12 December 2020

Differential control of the tyrosine kinases Lyn and Syk by the two signaling chains of the high affinity immunoglobulin E receptor

1 reference

12 December 2020

Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia

1 reference

12 December 2020

Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis

1 reference

12 December 2020

The human antibacterial cathelicidin, hCAP-18, is synthesized in myelocytes and metamyelocytes and localized to specific granules in neutrophils

1 reference

12 December 2020

Fc gamma receptor IIB on dendritic cells enforces peripheral tolerance by inhibiting effector T cell responses

1 reference

12 December 2020

Sweet and sour: the role of glycosylation for the anti-inflammatory activity of immunoglobulin G.

1 reference

12 December 2020

The heterogeneity of azurophil granules in neutrophil promyelocytes: immunogold localization of myeloperoxidase, cathepsin G, elastase, proteinase 3, and bactericidal/permeability increasing protein.

1 reference

12 December 2020

Natural killer cell and granulocyte Fc gamma receptor III (CD16) differ in membrane anchor and signal transduction

1 reference

12 December 2020

Analysis of signal transduction pathways regulating cytokine-mediated Fc receptor activation on human eosinophils

1 reference

12 December 2020

Identifiers

DOI

10.1111/IMR.12482

1 reference

9 September 2017

1 reference