Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. (Q51926211)

17 April 2018

title

Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. (English)

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Will Fischer

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Tanmoy Bhattacharya

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Beatrice H Hahn

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Barton Haynes

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Bruce D Walker

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Norman L. Letvin

object named as

Norman L Letvin

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Karina Yusim

object named as

Karina Yusim

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Robert K Funkhouser

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Robert Funkhouser

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author name string

Simon Perkins

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James Theiler

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Carla Kuiken

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language of work or name

English

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publication date

24 December 2006

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17 April 2018

published in

Nature Medicine

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volume

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issue

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page(s)

100-106

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cites work

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Human Immunodeficiency Virus Type 1 Subtype B Ancestral Envelope Protein Is Functional and Elicits Neutralizing Antibodies in Rabbits Similar to Those Elicited by a Circulating Subtype B Envelope

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Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen

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Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences

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HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response.

21 January 2018

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Clonal breadth of the HIV-1-specific T-cell receptor repertoire in vivo as determined by subtractive analysis

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CD8+ T cell epitope-flanking mutations disrupt proteasomal processing of HIV-1 Nef.

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A new variant cytotoxic T lymphocyte escape mutation in HLA-B27-positive individuals infected with HIV type 1.

21 January 2018

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Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities

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HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity

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Improved vaccine protection from simian AIDS by the addition of nonstructural simian immunodeficiency virus genes

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HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway

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Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load

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Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

21 January 2018

1 reference

Immunogenicity of Multiple Gene and Clade Human Immunodeficiency Virus Type 1 DNA Vaccines

21 January 2018

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Multiclade human immunodeficiency virus type 1 envelope immunogens elicit broad cellular and humoral immunity in rhesus monkeys

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1 reference

The role of T cell antagonism and original antigenic sin in genetic immunization

21 January 2018

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DNA multi-CTL epitope vaccines for HIV and Plasmodium falciparum: immunogenicity in mice.

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1 reference

Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination

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1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Urgently needed: a filter for the HIV-1 vaccine pipeline

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NM1461

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17 April 2018

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17 April 2018