Acridone alkaloids
Appearance
![](http://178.128.105.246/content-http-upload.wikimedia.org/wikipedia/commons/thumb/9/94/Acridone_Structural_Formula_V1.svg/220px-Acridone_Structural_Formula_V1.svg.png)
![](http://178.128.105.246/content-http-upload.wikimedia.org/wikipedia/commons/thumb/5/50/Ruta_graveolens_LC0061.jpg/220px-Ruta_graveolens_LC0061.jpg)
Acridone alkaloids are natural products derived from acridone.[1]
Occurrence
[edit]Acridone alkaloids are found in bark, wood, leaves and roots of rue plants,[1] especially in roots and suspension cultures of rue.[2]
Examples
[edit]This group is named after the acridone. Further members are acronycin, melicopicine and rutacridone, among others:[1][3]
Acronycin Melicopicine Rutacridon
Properties
[edit]Many acridone alkaloids are methylated on the nitrogen atom and also have two oxygen functional groups, which can be free, alkylated or incorporated into rings. Acridone alkaloids show a blue-green fluorescence so that they can be detected with UV light. Some alkaloids of this group are effective against malaria pathogens. Furthermore, acronycin inhibits cell division.[2]
References
[edit]- ^ a b c Entry on Acridone. at: Römpp Online. Georg Thieme Verlag, retrieved 21 April 2020.
- ^ a b R. Hänsel, O.Sticher (2007), Pharmakognosie Phytopharmazie (in German) (8 ed.), Heidelberg: Springer Medizin Verlag, pp. 101,1326, ISBN 9783540265085
- ^ "Acridone alkaloid biosynthesis". Archived from the original on 12 June 2020. Retrieved 22 April 2020.