Avicularin
Appearance
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Names | |
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IUPAC name
3-(α-L-Arabinofuranosyloxy)-3′,4′,5,7-tetrahydroxyflavone
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Systematic IUPAC name
3-{[(2S,3R,4R,5S)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one | |
Other names
quercetin-3-O-α-L-arabinofuranoside
quercetin-3-O-α-arabinofuranoside Avicularine Avicularoside Fenicularin Quercetin 3-alpha-L-arabinofuranoside | |
Identifiers | |
3D model (JSmol)
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CompTox Dashboard (EPA)
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Properties | |
C20H18O11 | |
Molar mass | 434.35 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Avicularin is a bio-active flavonol isolated from a number of plants including Polygonum aviculare,[1] Rhododendron aureum and Taxillus kaempferi.[2]
It suppresses lipid accumulation through repression of C/EBPα-activated GLUT4-mediated glucose uptake in 3T3-L1 cells.[2]
References
[edit]- ^ LC Method for Analysis of Three Flavonols in Rat Plasma and Urine after Oral Administration of Polygonum aviculare Extract. Fuquan Xu, Huashi Guan, Guoqiang Li and Hongbing Liu, Chromatographia, June 2009, Volume 69, Issue 11-12, pages 1251-1258, doi:10.1365/s10337-009-1088-x
- ^ a b Avicularin, a plant flavonoid, suppresses lipid accumulation through repression of C/EBPα-activated GLUT4-mediated glucose uptake in 3T3-L1 cells. Fujimori K and Shibano M, J Agric Food Chem., 29 May 2013, volume 61, issue 21, pages 5139-5147, doi:10.1021/jf401154c, PMID 23647459