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Beta-amyrin 24-hydroxylase

From Wikipedia, the free encyclopedia
Beta-amyrin 24-hydroxylase
Identifiers
EC no.1.14.99.43
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

Beta-amyrin 24-hydroxylase (EC 1.14.99.43, sophoradiol 24-hydroxylase, CYP93E1) is an enzyme with systematic name beta-amyrin,AH2:oxygen oxidoreductase (24-hydroxylating).[1] This enzyme catalyses the following chemical reaction

(1) beta-amyrin + AH2 + O2 24-hydroxy-beta-amyrin + A + H2O
(2) sophoradiol + AH2 + O2 24-hydroxysophoradiol + A + H2O

Beta-amyrin 24-hydroxylase is heme-thiolate protein (P-450).

References

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  1. ^ Shibuya M, Hoshino M, Katsube Y, Hayashi H, Kushiro T, Ebizuka Y (March 2006). "Identification of beta-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay". The FEBS Journal. 273 (5): 948–59. doi:10.1111/j.1742-4658.2006.05120.x. PMID 16478469.
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