Chebulic acid
Appearance
![]() Chebulic acid, according to Lee, 2010.[1]
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![]() Chebulic acid, according to Klika, 2004.[2]
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Names | |
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IUPAC name
(2R)-2-[(3S)-3-carboxy-5,6,7-trihydroxy-1-oxo-3,4-ihydroisochromen-4-yl]butanedioic acid
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Other names
Chebuloyl
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C14H12O11 | |
Molar mass | 356.23 g/mol |
Appearance | Brown powder |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chebulic acid is a phenolic compound isolated from the ripe fruits of Terminalia chebula.[3]
This compound possesses an isomer, neochebulic acid.
Chebulic acid is a component of transformed ellagitannins such as chebulagic acid or chebulinic acid.
References
[edit]- ^ Lee, H. S.; Koo, Y. C.; Suh, H. J.; Kim, K. Y.; Lee, K. W. (2010). "Preventive effects of chebulic acid isolated from Terminalia chebula on advanced glycation endproduct-induced endothelial cell dysfunction". Journal of Ethnopharmacology. 131 (3): 567–574. doi:10.1016/j.jep.2010.07.039. PMID 20659546.
- ^ The structural and conformational analyses and antioxidant activities of chebulinic acid and its thrice-hydrolyzed derivative, 2,4-chebuloyl-β-D-glucopyranoside, isolated from the fruit of Terminalia chebula. Karel D. Klika, Ammar Saleem, Jari Sinkkonen, Marja Kähkönen, Jyrki Loponen, Petri Tähtinen and Kalevi Pihlaja, ARKIVOC 2004 (vii) 83-105
- ^ Lee, H. S.; Jung, S. H.; Yun, B. S.; Lee, K. W. (2006). "Isolation of chebulic acid from Terminalia chebula Retz. And its antioxidant effect in isolated rat hepatocytes". Archives of Toxicology. 81 (3): 211–218. doi:10.1007/s00204-006-0139-4. PMID 16932919. S2CID 25751621.