Neoschizomer
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This article possibly contains original research. (December 2010) |
Neoschizomers are restriction enzymes that recognize the same nucleotide sequence as their prototype but cleave at a different site. In some special applications this is a very helpful feature.
For example:Prototype MaeII A^CGT produces DNA fragments with a 2-base 5' extension Neoschizomer TaiI ACGT^ produces DNA fragments with a 4-base 3' extension
Prototype ApaI GGGCC^C produces DNA fragments with a 4-base 3' extension Neoschizomer Bsp120I G^GGCCC produces DNA fragments with a 4-base 5' extension
There are also other pairs of neoschizomers.
Neoschizomers are a subset of isoschizomers.
References
[edit]- Rebase restriction enzyme database, http://rebase.neb.com/rebase/
See also
[edit]Wikidata has the property:
- neoschizomer (P4875) (see uses)