Jump to content

OR3A2

From Wikipedia, the free encyclopedia
OR3A2
Identifiers
AliasesOR3A2, OLFRA04, OR17-14, OR17-228, OR228, olfactory receptor family 3 subfamily A member 2
External IDsMGI: 3030244; HomoloGene: 68262; GeneCards: OR3A2; OMA:OR3A2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002551

NM_146707

RefSeq (protein)

NP_002542

NP_666918

Location (UCSC)Chr 17: 3.28 – 3.39 MbChr 11: 74.22 – 74.23 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 3A2 is a protein that in humans is encoded by the OR3A2 gene.[5][6][7]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[7]

See also

[edit]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000221882Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063116Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Glusman G, Clifton S, Roe B, Lancet D (Feb 1997). "Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: recombinatorial events affecting receptor diversity". Genomics. 37 (2): 147–60. doi:10.1006/geno.1996.0536. PMID 8921386.
  6. ^ Glusman G, Sosinsky A, Ben-Asher E, Avidan N, Sonkin D, Bahar A, Rosenthal A, Clifton S, Roe B, Ferraz C, Demaille J, Lancet D (Apr 2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics. 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334. S2CID 23416814.
  7. ^ a b "Entrez Gene: OR3A2 olfactory receptor, family 3, subfamily A, member 2".

Further reading

[edit]
[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.