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GRIN3A

From Wikipedia, the free encyclopedia
GRIN3A
Identifiers
AliasesGRIN3A, GluN3A, NMDAR-L, NR3A, glutamate ionotropic receptor NMDA type subunit 3A, NMDAR3A
External IDsOMIM: 606650; MGI: 1933206; HomoloGene: 128613; GeneCards: GRIN3A; OMA:GRIN3A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_133445

NM_001033351
NM_001276355

RefSeq (protein)

NP_597702

NP_001028523
NP_001263284

Location (UCSC)Chr 9: 101.57 – 101.74 MbChr 4: 49.66 – 49.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Glutamate [NMDA] receptor subunit 3A is a protein that in humans is encoded by the GRIN3A gene.[5]

Function

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This gene encodes a subunit of the N-methyl-D-aspartate (NMDAR) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity.[5]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198785Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039579Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A".

Further reading

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