pravastatin &nbsp; ingelesa (Q1240093)

pravastatin (ingelesa)

(3R,5R)-7-[(1S,2S,6S,8S,8aS)-6-hydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid ^ingelesa

4 urria 2016

stereoisomer of ^ingelesa

2 erreferentzia

based on heuristic ^ingelesa

inferred from InChIKey ^ingelesa

based on heuristic ^ingelesa

inferred from InChI ^ingelesa

6'-epipravastatin ^ingelesa

Erreferentzia bat

based on heuristic ^ingelesa

inferred from InChI ^ingelesa

(3S,5S)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid ^ingelesa

Erreferentzia bat

based on heuristic ^ingelesa

inferred from InChI ^ingelesa

formula kimikoa

C₂₃H₃₆O₇

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pravastatin (ingelesa)

19 azaroa 2016

SMILES

CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)O)O)O)O

Erreferentzia bat

pravastatin (ingelesa)

19 azaroa 2016

isomeric SMILES ^ingelesa

CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)O)O)O)O

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pravastatin (ingelesa)

https://www.whocc.no/atc_ddd_index/?code=C10AA03

19 azaroa 2016

defined daily dose ^ingelesa

30 miligramo

route of administration ^ingelesa

aho emate

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URL erreferentzia

active ingredient in ^ingelesa

Pravachol ^ingelesa

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RxNorm ^ingelesa

RxNorm ID ^ingelesa

203333

14 otsaila 2018

World Health Organisation international non-proprietary name ^ingelesa

pravastatin (ingelesa)

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ChEBI-ren identifikatzailea

ChEBI ^ingelesa

63618

ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinium ^ingelesa

pravastatin (ingelesa)

4 urria 2016

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Aspergillus sclerotiorum

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Lovastatin Analogues from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178. ^ingelesa

medical condition treated ^ingelesa

hipertriglizeridemia

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NDF-RT ^ingelesa

NDF-RT ID ^ingelesa

arteria koronarioetako gaixotasun

13 abendua 2016

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NDF-RT ^ingelesa

NDF-RT ID ^ingelesa

13 abendua 2016

familial hyperlipidemia ^ingelesa

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NDF-RT ^ingelesa

NDF-RT ID ^ingelesa

13 abendua 2016

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NDF-RT ^ingelesa

NDF-RT ID ^ingelesa

13 abendua 2016

lipedema ^ingelesa

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Drug Indications Extracted from FAERS ^ingelesa

2 urria 2018

acute myeloid leukemia ^ingelesa

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Drug Indications Extracted from FAERS ^ingelesa

2 urria 2018

rare dyslipidemia ^ingelesa

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Drug Indications Extracted from FAERS ^ingelesa

2 urria 2018

significant drug interaction ^ingelesa

ciprofibrate ^ingelesa

side effect ^ingelesa

rhabdomyolysis ^ingelesa

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A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

gemfibrozil ^ingelesa

side effect ^ingelesa

rhabdomyolysis ^ingelesa

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established ^ingelesa

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

fenofibrate ^ingelesa

side effect ^ingelesa

rhabdomyolysis ^ingelesa

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A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

(2R)-daptomycin ^ingelesa

side effect ^ingelesa

rhabdomyolysis ^ingelesa

Erreferentzia bat

hipotetikoki

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

Koltxizina

side effect ^ingelesa

rhabdomyolysis ^ingelesa

Erreferentzia bat

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

bezafibrate ^ingelesa

side effect ^ingelesa

rhabdomyolysis ^ingelesa

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hipotetikoki

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

fenofibrate ^ingelesa

side effect ^ingelesa

Erreferentzia bat

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

ciprofibrate ^ingelesa

side effect ^ingelesa

Erreferentzia bat

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

Koltxizina

side effect ^ingelesa

Erreferentzia bat

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

(2R)-daptomycin ^ingelesa

side effect ^ingelesa

Erreferentzia bat

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

bezafibrate ^ingelesa

side effect ^ingelesa

Erreferentzia bat

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

Klaritromizina

side effect ^ingelesa

rhabdomyolysis ^ingelesa

Erreferentzia bat

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

Klaritromizina

side effect ^ingelesa

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A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

ziklosporina

side effect ^ingelesa

rhabdomyolysis ^ingelesa

Erreferentzia bat

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

ziklosporina

side effect ^ingelesa

Erreferentzia bat

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

gemfibrozil ^ingelesa

side effect ^ingelesa

miopatia

Erreferentzia bat

established ^ingelesa

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

Eritromizina

side effect ^ingelesa

rhabdomyolysis ^ingelesa

Erreferentzia bat

hipotetikoki

fisikoki honekin elkarrekintza du

A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

Eritromizina

side effect ^ingelesa

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A reference set of clinically relevant adverse drug-drug interactions ^ingelesa

3-hydroxy-3-methylglutaryl-CoA reductase ^ingelesa

subjektuak duen rola

Entzimen inhibitzaile

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IUPHAR/BPS Guide to PHARMACOLOGY ^ingelesa

Guide to Pharmacology Ligand ID ^ingelesa

2953

17 abuztua 2016

Solute carrier organic anion transporter family member 1B1 ^ingelesa

subjektuak duen rola

Entzimen inhibitzaile

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IUPHAR/BPS Guide to PHARMACOLOGY ^ingelesa

Guide to Pharmacology Ligand ID ^ingelesa

2953

17 abuztua 2016

pregnancy category ^ingelesa

Australian pregnancy category D ^ingelesa

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iturria

Ingelesezko Wikipedia

US pregnancy category X ^ingelesa

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iturria

Ingelesezko Wikipedia

LiverTox likelihood score ^ingelesa

LiverTox toxicity likelihood category B ^ingelesa

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LiverTox ^ingelesa

https://www.ncbi.nlm.nih.gov/books/n/livertox/Pravastatin

8 apirila 2021

URL erreferentzia

5 abuztua 2017

2 erreferentzia

NDF-RT ^ingelesa

NDF-RT ID ^ingelesa

5 martxoa 2018

Medical Subject Headings

MeSH identifikadorea

D017035

15 martxoa 2018

anticholesteremic agents ^ingelesa

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Medical Subject Headings

MeSH identifikadorea

D017035

InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1

15 martxoa 2018

Commons-eko kategoria

Pravastatin

0 erreferentzia

Identifikatzaileak

InChI

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pravastatin (ingelesa)

19 azaroa 2016

2 erreferentzia

pravastatin (ingelesa)

19 azaroa 2016

ChEBI release 2020-09-01 ^ingelesa

CAS zenbakia

81093-37-0

2 erreferentzia

Global Substance Registration System ^ingelesa

UNII

KXO2KT9N0G

pravastatin (ingelesa)

19 azaroa 2016

CAS Common Chemistry ^ingelesa

https://commonchemistry.cas.org/detail?cas_rn=81093-37-0

8 apirila 2021

URL erreferentzia

ChemSpider-ren identifikatzailea

49398

Erreferentzia bat

ChemSpider-ren identifikatzailea

ChemSpider ^ingelesa

49398

Pravastatin (ingelesa)

19 azaroa 2016

2 erreferentzia

pravastatin (ingelesa)

19 azaroa 2016

Reaxys registry number ^ingelesa

4825538

Erreferentzia bat

ChEBI-ren identifikatzailea

ChEBI ^ingelesa

63618

pravastatin (ingelesa)

ChEBI-ren identifikatzailea

4 urria 2016

63618

mapping relation type ^ingelesa

exact match ^ingelesa

2 erreferentzia

ChEMBL-en identifikatzailea

ChEMBL ^ingelesa

CHEMBL1144

PRAVASTATIN (ingelesa)

19 azaroa 2016

ChEMBL-en identifikatzailea

International Chemical Identifier ^ingelesa

InChI

CHEMBL1144

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ChEMBL-en identifikatzailea

ChEMBL ^ingelesa

CHEMBL1144

PRAVASTATIN (ingelesa)

19 azaroa 2016

SureChEMBL ID ^ingelesa

SCHEMBL1117

2 erreferentzia

based on heuristic ^ingelesa

inferred from InChIKey ^ingelesa

UniChem compound ID ^ingelesa

385404

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splash10-00di-0002900000-bd7fd66d793ae64426ff

UniChem ^ingelesa

MassBank accession ID ^ingelesa

0 erreferentzia

0 erreferentzia

0 erreferentzia

0 erreferentzia

0 erreferentzia

0 erreferentzia

0 erreferentzia

0 erreferentzia

0 erreferentzia

0 erreferentzia

0 erreferentzia

0 erreferentzia

0 erreferentzia

0 erreferentzia

0 erreferentzia

SPLASH ^ingelesa

0 erreferentzia

splash10-0udi-4809000000-0ed5a8797dfc49ecf5af

0 erreferentzia

splash10-0udi-2900000000-91b125182ce5d90f16ab

0 erreferentzia

splash10-0udi-1900000000-e8fc6384260de93c5aa8

0 erreferentzia

splash10-0udi-1900000000-11e99968bc0ba393b6f9

0 erreferentzia

splash10-0udi-4900000000-0e4265e6dc1468c1471d

0 erreferentzia

splash10-00di-0002900000-8795ee00dded0ef8be48

0 erreferentzia

splash10-0udi-3709000000-aa45be15af0471c0a46e

0 erreferentzia

splash10-0udi-2900000000-5617409991f5c58e5130

0 erreferentzia

splash10-0udi-2900000000-2bf5c13979a639625d1c

0 erreferentzia

splash10-0udi-2900000000-9a233e521607e82ab7a0

0 erreferentzia

splash10-0udi-0900000000-2083dfbb67bf2b03ccf9

0 erreferentzia

splash10-0uk9-0009000000-4b2c09a295ba7f3ce41b

0 erreferentzia

splash10-00di-0607900000-e57e263ad3f74bfda195

0 erreferentzia

HSDB ID ^ingelesa

8368

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Hazardous Substances Data Bank ^ingelesa

HSDB ID ^ingelesa

8368

argitaratze-data

28 urria 2019

Pravastatin (ingelesa)

10 maiatza 2021

DSSTox substance ID ^ingelesa

DTXSID6023498

2 erreferentzia

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^ingelesa

DSSTOX compound identifier ^ingelesa

DTXCID003498

0 erreferentzia

LiverTox ID ^ingelesa

Pravastatin

0 erreferentzia

EC zenbakia

689-360-3

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ECHA Substance Infocard database ^ingelesa

ECHA Substance Infocard ID ^ingelesa

100.216.225

27 abendua 2018

+)-(3R,5R)-3,5-Dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(S)-2-methylbutyryloxy]-1,2,6,7,8,8a-hexahydro-1-naphthyl]-heptanoic acid (ingelesa)

quotation ^ingelesa

CAS no.: 81093-37-0 (ingelesa)

ECHA Substance Infocard ID ^ingelesa

100.216.225

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ECHA Substance Infocard database ^ingelesa

ECHA Substance Infocard ID ^ingelesa

100.216.225

27 abendua 2018

+)-(3R,5R)-3,5-Dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(S)-2-methylbutyryloxy]-1,2,6,7,8,8a-hexahydro-1-naphthyl]-heptanoic acid (ingelesa)

quotation ^ingelesa

CAS no.: 81093-37-0 (ingelesa)

ATC kodea

C10AA03

Erreferentzia bat

DrugBank ^ingelesa

DrugBank ID ^ingelesa

00175