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3,4-Dihydroxymandelic acid

From Wikipedia, the free encyclopedia
3,4-Dihydroxymandelic acid
Names
Preferred IUPAC name
(3,4-Dihydroxyphenyl)(hydroxy)acetic acid
Other names
2-(3,4-Dihydroxyphenyl)-2-hydroxyacetic acid
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.011.154 Edit this at Wikidata
KEGG
MeSH 3,4-dihydroxymandelic+acid
UNII
  • InChI=1S/C8H8O5/c9-5-2-1-4(3-6(5)10)7(11)8(12)13/h1-3,7,9-11H,(H,12,13) checkY
    Key: RGHMISIYKIHAJW-UHFFFAOYSA-N checkY
  • InChI=1/C8H8O5/c9-5-2-1-4(3-6(5)10)7(11)8(12)13/h1-3,7,9-11H,(H,12,13)
    Key: RGHMISIYKIHAJW-UHFFFAOYAB
  • O=C(O)C(O)c1cc(O)c(O)cc1
Properties
C8H8O5
Molar mass 184.14612
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

3,4-Dihydroxymandelic acid (DHMA, DOMA) is a metabolite of norepinephrine.[1]

Norepinephrine degradation. 3,4-Dihydroxymandelic acid is shown at right. Enzymes are shown in boxes.[2]

References

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  1. ^ Ley JP; Engelhart K; Bernhardt J; Bertram HJ (October 2002). "3,4-Dihydroxymandelic acid, a noradrenalin metabolite with powerful antioxidative potential". J. Agric. Food Chem. 50 (21): 5897–902. doi:10.1021/jf025667e. PMID 12358456.
  2. ^ Figure 11-4 in: Rod Flower; Humphrey P. Rang; Maureen M. Dale; Ritter, James M. (2007). Rang & Dale's pharmacology. Edinburgh: Churchill Livingstone. ISBN 978-0-443-06911-6.