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AGXT2

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AGXT2
Identifiers
AliasesAGXT2, AGT2, DAIBAT, alanine--glyoxylate aminotransferase 2, BAIBA
External IDsOMIM: 612471; MGI: 2146052; HomoloGene: 12887; GeneCards: AGXT2; OMA:AGXT2 - orthologs
EC number2.6.1.40
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001306173
NM_031900

NM_001031851
NM_001310735
NM_001310736

RefSeq (protein)

NP_001293102
NP_114106

NP_001027021
NP_001297664
NP_001297665

Location (UCSC)Chr 5: 35 – 35.05 MbChr 15: 10.36 – 10.41 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The human AGXT2 gene encodes the protein Alanine—glyoxylate aminotransferase 2. [5]

Function

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The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000113492Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000089678Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Alanine--glyoxylate aminotransferase 2". Retrieved 2014-01-12.
  6. ^ [provided by RefSeq, Dec 2008]. ##Evidence-Data-START## Transcript exon combination :: AJ292204.1, AB193309.1 [ECO:0000332] RNAseq introns  :: mixed/partial sample support ERS025084, ERS025088 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.