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ANXA8L2

From Wikipedia, the free encyclopedia
ANXA8L1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesANXA8L1, ANXA8, ANXA8L2, VAC-beta, bA145E20.2, annexin A8-like 1, annexin A8 like 1
External IDsMGI: 1201374; HomoloGene: 20393; GeneCards: ANXA8L1; OMA:ANXA8L1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001039801
NM_001098845
NM_001278923
NM_001278924
NM_001630

NM_001281845
NM_013473

RefSeq (protein)

NP_001268774
NP_038501

Location (UCSC)Chr 10: 46.38 – 46.39 MbChr 14: 33.81 – 33.82 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Annexin A8-like protein 2 is a protein that in humans is encoded by the ANXA8L2 gene.[5]

This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000264230Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021950Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: ANXA8 annexin A8".
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Further reading

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