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Ae binding protein 1

From Wikipedia, the free encyclopedia
AEBP1
Identifiers
AliasesAEBP1, ACLP, AE binding protein 1
External IDsOMIM: 602981; MGI: 1197012; HomoloGene: 878; GeneCards: AEBP1; OMA:AEBP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001129

NM_001291857
NM_009636

RefSeq (protein)

NP_001120

NP_001278786
NP_033766

Location (UCSC)Chr 7: 44.1 – 44.11 MbChr 11: 5.81 – 5.82 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

AE binding protein 1 is a protein that in humans is encoded by the AEBP1 gene.[5]

Function

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AE binding protein 1 is a member of carboxypeptidase A protein family. The protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that the AEBP1 gene that encodes the protein functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106624Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020473Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: AE binding protein 1".
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Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.