Jump to content

Frizzled-5

From Wikipedia, the free encyclopedia
FZD5
Identifiers
AliasesFZD5, C2orf31, HFZ5, frizzled class receptor 5
External IDsOMIM: 601723; MGI: 108571; HomoloGene: 2590; GeneCards: FZD5; OMA:FZD5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030804
NM_003468

NM_001033193
NM_001042659
NM_022721

RefSeq (protein)

NP_003459

NP_001036124
NP_073558

Location (UCSC)Chr 2: 207.76 – 207.77 MbChr 1: 64.77 – 64.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Frizzled-5 (Fz-5) is a protein that in humans is encoded by the FZD5 gene.[5][6][7]

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. Fz-5 is believed to be the receptor for the Wnt5A ligand.[7]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163251Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045005Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Wang Y, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J (Jun 1996). "A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled". J Biol Chem. 271 (8): 4468–76. doi:10.1074/jbc.271.8.4468. PMID 8626800.
  6. ^ Saitoh T, Hirai M, Katoh M (Jun 2001). "Molecular cloning and characterization of human Frizzled-5 gene on chromosome 2q33.3-q34 region". Int J Oncol. 19 (1): 105–10. doi:10.3892/ijo.19.1.105. PMID 11408929.
  7. ^ a b "Entrez Gene: FZD5 frizzled homolog 5 (Drosophila)".

Further reading

[edit]
[edit]
  • "Frizzled Receptors: FZD5". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2016-06-25. Retrieved 2008-12-04.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.