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Giles (bacteriophage)

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Mycobacterium phage Giles
Virus classification Edit this classification
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Uroviricota
Class: Caudoviricetes
Order: Caudovirales
Family: Siphoviridae
Genus: Gilesvirus
Species:
Mycobacterium phage Giles

Giles is a bacteriophage that infects Mycobacterium smegmatis bacteria.[1] The genome of this phage is very different from that of other mycobacteriophages and is highly mosaic. More than half of its predicted genes are novel and are not seen in other species.[2][3]

References

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  1. ^ Morris, P; Marinelli, LJ; Jacobs-Sera, D; Hendrix, RW; Hatfull, GF (March 2008). "Genomic characterization of mycobacteriophage Giles: evidence for phage acquisition of host DNA by illegitimate recombination". Journal of Bacteriology. 190 (6): 2172–82. doi:10.1128/JB.01657-07. PMC 2258872. PMID 18178732.
  2. ^ Hatfull, GF; Jacobs-Sera, D; Lawrence, JG; Pope, WH; Russell, DA; Ko, CC; Weber, RJ; Patel, MC; Germane, KL; Edgar, RH; Hoyte, NN; Bowman, CA; Tantoco, AT; Paladin, EC; Myers, MS; Smith, AL; Grace, MS; Pham, TT; O'Brien, MB; Vogelsberger, AM; Hryckowian, AJ; Wynalek, JL; Donis-Keller, H; Bogel, MW; Peebles, CL; Cresawn, SG; Hendrix, RW (Mar 19, 2010). "Comparative genomic analysis of 60 Mycobacteriophage genomes: genome clustering, gene acquisition, and gene size". Journal of Molecular Biology. 397 (1): 119–43. doi:10.1016/j.jmb.2010.01.011. PMC 2830324. PMID 20064525.
  3. ^ Dedrick, Rebekah M.; Marinelli, Laura J.; Newton, Gerald L.; Pogliano, Kit; Pogliano, Joseph; Hatfull, Graham F. (May 2013). "Functional requirements for bacteriophage growth: gene essentiality and expression in mycobacteriophage Giles". Molecular Microbiology. 88 (3): 577–589. doi:10.1111/mmi.12210. PMC 3641587. PMID 23560716.
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