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Neldazosin

From Wikipedia, the free encyclopedia
Neldazosin
Names
IUPAC name
1-[4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-3-hydroxybutan-1-one
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C18H25N5O4/c1-11(24)8-16(25)22-4-6-23(7-5-22)18-20-13-10-15(27-3)14(26-2)9-12(13)17(19)21-18/h9-11,24H,4-8H2,1-3H3,(H2,19,20,21)
    Key: IOSMPEJNAQZKJT-UHFFFAOYSA-N
  • CC(CC(=O)N1CCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)N)OC)OC)O
Properties
C18H25N5O4
Molar mass 375.429 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Neldazosin is an α-adrenoreceptor antagonist.[1]

References

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  1. ^ Boido, Alessandro; Budriesi, Roberta; Boido, Caterina Canu; Ioan, Pierfranco; Terranova, Emanuela; Chiarini, Alberto; Sparatore, Fabio (2005). "Alpha1- and alpha2-adrenoreceptor antagonist profiles of 1- and 2-[omega-(4-arylpiperazin-1-yl)alkyl]-1,2,3-benzotriazoles". Chemistry & Biodiversity. 2 (10): 1290–304. doi:10.1002/cbdv.200590100. PMID 17191929. S2CID 94008789.