Phenothiazinum
Appearance
![](http://178.128.105.246/host-http-upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Phenothiazine.svg/220px-Phenothiazine.svg.png)
Phenothiazinum est in chemia compositum organicum formulae S(C6H4)2NH. Nonnulla phenothiazinorum medicamenta antipsychotica ad schizophreniam therapiam nota sunt[1].
Structura chemica
[recensere | fontem recensere]Structura phenothiazini est 10H-di-benzo-[b,e]-1,4-thiazinum.
Medicamenta antipsychotica
[recensere | fontem recensere]Medicamenta antipsychotica cum phenothiazino in greges tres dividuntur: composita aliphatica, piperidina, piperazina.
Grex | Effectus autonomicus | Exemplum | Sedativum | Reactio adversa |
Composita aliphatica | ||||
moderate | Chlorpromazinum | forte | moderate | |
Promazinum | moderate | moderate | ||
Triflupromazinum | forte | moderate/forte | ||
Laevomepromazinum | fortissime | minime | ||
Piperidina | fuerte | Mesoridazinum | forte | lente |
Thioridazinum | forte | lente | ||
Piperazina | lente | Fluphenazinum | lente/moderate | forte |
Perphenazinum | lente/moderate | forte | ||
Prochlorperazinum | ||||
Trifluoperazinum | moderate | forte |
Effectus biologici
[recensere | fontem recensere]![](http://178.128.105.246/host-http-upload.wikimedia.org/wikipedia/commons/thumb/e/e0/Phototoxic_reaction_from_Ketoprofen.jpg/220px-Phototoxic_reaction_from_Ketoprofen.jpg)
Apud homines et animales phenothiazina effectus phototoxicos perficiunt: Phenothiazinum una cum luce reactionem adversariam cutaneam provocare possunt.
Notae
[recensere | fontem recensere]- ↑ Jaszczyszyn A, Gasiorowski1 K, Swiatek P, Malinka W, Cieslik-Boczula K, Petrus J, Czarnik-Matusewicz B (2012). "Chemical structure of phenothiazines and their biological activity". Pharmacol Rep 64: 16-23