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EIF1AY

From Wikipedia, the free encyclopedia
EIF1AY
Identifiers
AliasesEIF1AY, eIF-4C, eukaryotic translation initiation factor 1A, Y-linked, eukaryotic translation initiation factor 1A Y-linked
External IDsOMIM: 400014; MGI: 1913485; HomoloGene: 100715; GeneCards: EIF1AY; OMA:EIF1AY - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004681
NM_001278612

NM_025437

RefSeq (protein)

NP_001265541
NP_004672

NP_079713

Location (UCSC)Chr Y: 20.58 – 20.59 MbChr X: 158.16 – 158.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Eukaryotic translation initiation factor 1A, Y-chromosomal is a protein that in humans is encoded by the EIF1AY gene.[5][6]

Like its X-chromosomal counterpart EIF1AX, it encodes an isoform of eukaryotic translation initiation factor 1A (EIF1A). EIF1A is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA. It has one amino acid difference (M50L) from EIF1AX.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198692Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000067194Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lahn BT, Page DC (Nov 1997). "Functional coherence of the human Y chromosome". Science. 278 (5338): 675–80. Bibcode:1997Sci...278..675L. doi:10.1126/science.278.5338.675. PMID 9381176.
  6. ^ a b "Entrez Gene: EIF1AY eukaryotic translation initiation factor 1A, Y-linked".

Further reading

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