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Somatostatin receptor 1

From Wikipedia, the free encyclopedia
SSTR1
Identifiers
AliasesSSTR1, SRIF-2, SS-1-R, SS1-R, SS1R, Somatostatin receptor 1
External IDsOMIM: 182451; MGI: 98327; HomoloGene: 820; GeneCards: SSTR1; OMA:SSTR1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001049

NM_009216

RefSeq (protein)

NP_001040

NP_033242

Location (UCSC)Chr 14: 38.21 – 38.21 MbChr 12: 58.26 – 58.26 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Somatostatin receptor type 1 is a protein that in humans is encoded by the SSTR1 gene.[5][6]

Function

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Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. The encoded protein is a member of the superfamily of somatostatin receptors having seven transmembrane segments, and is expressed in highest levels in jejunum and stomach.[6]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000139874Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035431Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI (February 1993). "Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms". Genomics. 15 (2): 449–52. doi:10.1006/geno.1993.1088. PMID 8449518.
  6. ^ a b "Entrez Gene: SSTR1 somatostatin receptor 1".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.