Jump to content

NFIA

From Wikipedia, the free encyclopedia
NFIA
Identifiers
AliasesNFIA, CTF, NF-I/A, NF1-A, NFI-A, NFI-L, nuclear factor I A, BRMUTD
External IDsOMIM: 600727; MGI: 108056; HomoloGene: 4086; GeneCards: NFIA; OMA:NFIA - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001134673
NM_001145511
NM_001145512
NM_005595

NM_001122952
NM_001122953
NM_010905

RefSeq (protein)

NP_001128145
NP_001138983
NP_001138984
NP_005586

NP_001116424
NP_001116425
NP_035035

Location (UCSC)Chr 1: 60.87 – 61.46 MbChr 4: 97.66 – 98.01 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Nuclear factor 1 A-type is a protein that in humans is encoded by the NFIA gene.[5][6]

Function

[edit]

Nuclear factor I (NFI) proteins constitute a family of dimeric DNA-binding proteins with similar, and possibly identical, DNA-binding specificity. They function as cellular transcription factors and as replication factors for adenovirus DNA replication. Diversity in this protein family is generated by multiple genes, differential splicing, and heterodimerization.[supplied by OMIM][6]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162599Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028565Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Qian F, Kruse U, Lichter P, Sippel AE (July 1995). "Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH". Genomics. 28 (1): 66–73. doi:10.1006/geno.1995.1107. PMID 7590749.
  6. ^ a b "Entrez Gene: NFIA nuclear factor I/A".

Further reading

[edit]
[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.